最近获得资助的奖项

此页面列出了我们最近通过响应模式授予资金计划支持的由调查员领导的计划,项目和奖学金。

Select a funding committee to see what they have funded to date in 2021 (for Grant Award Letters issued up to March 2022):

生物标志物项目奖

格拉斯哥大学Mhairi Copland教授
Evaluation of key Biomarkers for the prediction of successful treatment-free remission (TFR) in chronic myeloid leukaemia

Professor Anthony Moorman, Newcastle University
评估小儿急性淋巴细胞白血病的综合和多生物标志物驱动的风险分层

Clinical Trial Awards

伯明翰大学达伦·哈格雷夫教授和帕梅拉·科恩斯教授
LOGGIC- Phase III, randomised, international multicentre trial for children and adolescents with low-grade glioma

Dr Christopher Fox, University of Southampton
优化基质作为新诊断的原发性中枢神经系统淋巴瘤的缓解诱导治疗 - 一项随机III期试验(Optimate试验)

彼得·霍斯金(Peter Hoskin)教授,加雷斯·格里菲斯(Gareth Griffiths)教授和阿尼亚·乔杜里(Ananya Choudhury),南安普敦大学
CRAIN:一项1B期临床试验,其剂量升级和ASTX660的剂量膨胀阶段与宫颈癌的标准自由基放射疗法结合

维多利亚·科伊尔博士和格拉斯哥大学丹尼尔·朗利教授
ASTFOX: A Phase I study of the IAP antagonist, ASTX660, in combination with standard of care FOLFOX chemotherapy in metastatic colorectal cancer

Mr Dirk Strauss, The Royal Marsden NHS Foundation Trust
EORTC-1809-STBSG:新辅助化疗的随机III期研究,然后是手术与仅针对高风险腹膜后肉瘤的患者(Strass 2)

Professor Simon Crabb and Professor Gareth Griffiths, University of Southampton
Aurora:膀胱和尿路鳞状细胞癌患者的atezolizumab - 单臂,开放标签,多中心,II期试验

Juanita Lopez博士,Christina Yap教授和Pascal Meier教授,癌症研究所
ASTEROID – A Phase I proof of concept study of ASTX660 in combination with PEmbROlizumab:utilizing triple IAP blockade as a strategy to maximize Immunogenic cell Death and the generation of a efficient adaptive immune response

Professor Jonathan Bridgewater, University College London
SAFIR-ABC10: molecular screening for precision medicine in advanced biliary cancers

Professor Bernadette Brennan and Professor Pamela Kearns, University of Birmingham
International clinical research programme to improve outcomes in newly diagnosed Ewing Sarcoma – Trial 1 (INTER-EWING-1)

伯明翰大学的格拉德斯通教授(AMOS)Burke和Lucinda Billingham教授
GLO-BNHL:对复发和难治性B-NHL的新型药物的全球研究

扩大

Dr Martin McCabe and Professor Keith Wheatley, University of Birmingham
REECUR:化学疗法的国际随机对照试验,用于治疗复发性和原发性EWING肉瘤

Prospective Sample Collection Awards

Professor Paul Lorigan, University of Manchester
From primary diagnosis to relapse or cure; a comprehensive sample collection from patients with stage II melanoma

June 2021

计划奖

New Programmes

Professor Christian Speck, Imperial College London
发现人解旋酶载荷控制的结构和机械原理及其在癌症中的正直

Kairbaan Hodivala-Dilke教授,伦敦皇后玛丽皇后
Exploiting the effects of low mural cell beta3-integrin in the control of cancer progression, therapy resistance and metastasis

Professor Jody Rosenblatt, King's College London
基础挤压:转移开始的新机制

Professor Trevor Graham, Queen Mary, University of London
MECCA: Metastatic Evolutionary dynamics of Colorectal Cancer

牛津大学/纽卡斯尔大学的Vincenzo D'Angiolella博士,史蒂夫·克利福德教授和亚历克斯·布洛克教授
KBTBD4在髓母细胞瘤中的新形态作用

Renewing Programmes

Professor Sergio Quezada, University College London
Development and evaluation of T- and innate-cell engagers driving agonistic activity independent of Fc/FcReceptor interactions

Professor Martin Humphries, University of Manchester
基质刚性作为胰腺导管腺癌进展的驱动力

Programme Foundation Awards

Dr Marc Mansour, University College London
在T细胞急性淋巴细胞白血病中解剖和利用增强子失调

Dr Dirk Sieger, University of Edinburgh
The role of microglia during the formation of neural network-like connections in glioma

Multidisciplinary Project Awards

伦敦帝国学院的Darryl Overby教授和Iain McNeish教授
卵巢癌个性化医学的“自上而下”器官

Dr Iain Dunlop, Imperial College London
免疫调节纳米疗法的生物物理设计

November 2021

计划奖

New Programmes

牛津大学Ulrike Gruneberg博士
Molecular Mechanisms Safeguarding Genome Stability

Dr Helfrid Hochegger, University of Sussex
利用新的细胞周期控制途径

爱丁堡大学史蒂文·波拉德教授
解剖胶质母细胞瘤中Sox蛋白的生化和细胞功能

Professor Edward Tate, Imperial College London
癌症中的蛋白质脂化:发现,机制和目标验证

Renewing Programmes

Professor Awen Gallimore, Cardiff University
Exploring the Relationship Between Antigen-Specific T Cells and the Tumour Microenvironment

Professor Chris Jones, Institute of Cancer Research
Targeting cellular diversity and interactivity in paediatric diffuse glioma

癌症研究所克里斯·洛德教授
Cancer vulnerabilities

癌症研究所教授艾伦·梅尔彻(Alan Melcher)兼凯文·哈灵顿教授
理解和利用组合肿瘤病毒和靶向药物免疫疗法的抗原性和辅助性

Programme Foundation Awards

Dr Christina Halsey, University of Glasgow
靶向代谢重编程,以开发出更有效和毒性的毒性治疗,以使中枢神经系统参与小儿急性淋巴细胞白血病

Cancer Immunology Project Awards

Dr Rebecca Gentek, University of Edinburgh
研究肥大细胞的起源以描绘它们在黑色素瘤进展中的功能

May 2021

Early Detection and Diagnosis Programme Awards

伦敦帝国学院乔治·汉娜教授
Augmented Response of vOlatile bioMarkers to detect oesophagogastric Adenocarcinoma (AROMA)

Early Detection and Diagnosis Project Awards

Dr Clare Rebbeck and Professor Gregory Hannon, University of Cambridge
使用“ DCIS进展时间表”来改善乳腺癌风险的临床测定法

Professor Francesca Palombo, Dr Nick Stone and Dr Oliver Old, University of Exeter
开发具有高机械和化学特异性的食管癌的早期检测和诊断的高级光学工具

Dr Maria Kyrgiou and Professor Zoltan Takats, Imperial College London
High-throughput laser-assisted Rapid Evaporative Ionisation Mass Spectrometry (Laser-REIMS) in the early detection and diagnosis of cervical pre-invasive disease

早期检测和诊断引物奖

Dr Charlene Greenwood, University of Keele
前列腺癌:基于组织微环境的高精度早期诊断

伦敦帝国学院的亚当·克里默(Adam Creamer)博士和利亚·弗雷尼特(Leah Frenette)博士
Magnetic, Fluorescent Nanoparticles for the Isolation of Blood Biomarkers in the Early Detection of Pancreatic Cancer

利兹大学莱斯利·史密斯博士和理查德·尼尔教授
Development of a myeloma case-finding approach for higher-risk patients: analysis of routine blood tests

斯旺西大学杰森·韦伯博士
Extracellular Vesicle Glycoproteins for Prostate Cancer Diagnosis (EVGlyProD)

Professor David Westhead, University of Leeds
预测卵泡淋巴瘤的早期进展

Dr Oluwafunmilola Ola and Dr Frankie Rawson, University of Nottingham
Point-of-care-Based Electrochemical Sensing for Human Papillomavirus Detection

剑桥大学Jamie Blundell博士
Exploiting the Immune System for Early Cancer Detection

Dr Richard Mair and Dr Rohitashwa Sinha, University of Cambridge
Early Detection with Urine and Cognitive Assessment Multiplex (The EDUCAM study)

Professor Marc Moncrieff, Dr Stuart Rushworth, Dr Mona Saad, Norfolk and Norwich University Hospital NHS Trust
Feasibility study investigating circulating peripheral mitochondrial DNA as a potential non-invasive biomarker for diagnosis and surveillance of high risk cutaneous melanoma

谢菲尔德大学克里斯托弗·托斯兰(Christopher Toseland)博士
用于早期检测癌症的单分子质量光度法

Dr Sourav Banerjee, University of Dundee
血液中的分泌磷蛋白酶作为胶质瘤的早期检测和风险分层生物标志物

November 2021

Early Detection and Diagnosis Programme Awards

Professor Daniel Murphy, Imperial College London, and Professor Marion MacFarlane, MRC Toxicology Unit
Integrated Analysis in Mouse and Man for Early Detection of Mesothelioma: IAMMED-Meso

Early Detection and Diagnosis Project Awards

Cruk Beatson研究所教授Sara Zanivan和Thomas Bird博士
将血浆氧化还原蛋白质学与机器学习相结合,以早期检测肝细胞癌

珍妮弗·莫顿教授和克鲁克·贝克森学院的萨拉·扎尼万教授
研究生物标志物在新发作糖尿病相关的糖尿病腺癌的基因工程小鼠模型中早期检测胰腺癌的早期检测

Professor Francesca Ciccarelli, King's College London
Early detection of oesophageal adenocarcinoma (OAC) from Barrett’s oesophagus (BO): defining genetic and microenvironmental drivers of BO-OAC transition

Dr Richard Bryan, University of Birmingham, and Professor Mieke Van Hemelrijck, King's College London
诊断膀胱癌 - 评估尿生物标志物测试在血液临床研究重新配置中的作用(“ BC-Recon”)

早期检测和诊断引物奖

伯明翰大学阿曼达·罗西特博士
Development of a patient-derived, mucosoid-microbiota model to identify novel gastric adenocarcinoma biomarkers triggered by the intestinal metaplasia-associated microbiota

Dr Ruchi Gupta, University of Birmingham
Lozenges for Early Detection of Cancer

剑桥大学Tristan Barrett博士和约克大学锡安TSE教授
Smartphone application for effective prostate cancer screening utilising machine learning- enhanced ultrasound PSA-density measurement

博士的人Hadjidemetriou,曼彻斯特大学er
非小细胞肺癌中支持纳米技术的多摩变液体活检

Professor Jason Davis, University of Oxford
乳腺癌screening using bimodal circulating tumour cell enrichment and detection

弗朗西斯·克里克学院(Francis Crick Institute)教授查尔斯·斯旺顿(Charles Swanton)和威廉·希尔(William Hill)博士
局部:空气污染对肺部癌症开始的影响

Dr Sean Knight, Professor Sarah Cartmell and Dr Katherine Finegan, University of Manchester
发现早期肺癌生物标志物的新平台

埃塞克斯大学的弗拉基米尔·蒂夫(Vladimir Teif)博士和爱丁堡大学的保罗·布伦南博士
Early cancer diagnostics and stratification based on nucleosome positioning reconstructed from cell-free DNA

May 2021

Project Grants

剑桥大学保罗·法罗亚教授
编码和非编码基因组的罕见种系遗传变异以及对卵巢癌的敏感性

汉娜·萨利斯(Hannah Sallis)博士,布里斯托尔大学
Smoking behaviours and transitions to vaping in early adulthood: Investigating predictors with longitudinal data

November 2021

Programme Grants

Professor Jamie Brown and Professor Lion Shahab, University College London
使用新颖的科学方法针对多个级别的“吸烟系统”

Professor Carolyn Taylor and Professor Sarah Darby, University of Oxford
癌症治疗的好处和风险

Project Grants

Antonis安东尼奥由于教授和教授道格拉斯·Easton, University of Cambridge
EMBRACE: Epidemiological study of mutation carriers in BRCA1, BRCA2 and other cancer susceptibility genes

Dr Paula Dhiman, University of Oxford
Sample size considerations for oncology studies developing and validating clinical predictions models using machine learning for binary outcomes in low dimensional data settings

May 2021

Career Development Fellowship

Dr Thomas MacVicar, CRUK Beatson Institute, Glasgow
靶向胰腺癌中的线粒体代谢物转运

Dr Diu Nguyen, Queen Mary, University of London
靶向转录后调节剂以根除急性髓样白血病中的白血病干细胞

职业机构奖

身为博士议会Ciriano,欧洲Bioinforma EMBL的tics Institute
Development and clinical validation of a multi-modal liquid biopsy test for cancer screening and monitoring using long-read sequencing technologies

临床医生奖学金

Dr Sally George, Institute of Cancer Research
ATRX改变在神经母细胞瘤的起源和治疗敏感性中的作用

Dr Marwan Kwok, University of Birmingham
Identifying tumour-immune interactions as determinants of clinical sequelae in chronic lymphocytic leukaemia

Pre-doctoral Research Bursaries

Dr Louisa Harding-Edgar, University of Glasgow
肺癌and early diagnosis after Covid-19: identifying the impact of remote consulting on lung cancer referral

纽卡斯尔大学汤姆·安德鲁博士
优化皮肤黑色素瘤中Amblor风险分类的深度学习模型

Mr Jonathan Pushpa-Rajah, University of Cambridge
Use of structural variants to detect recurrence of renal cancer via blood

Dr Alexandros Rampotas,伦敦大学学院
Towards developing a Chimeric Antigen Receptor (CAR) construct against mutated calreticulin

Postdoctoral Research Bursary

伊丽莎白·莫恩博士,儿童健康研究所/UCL
生成高级小儿甲状腺癌的个性化临床前模型

2021年12月

Career Development Fellowships

Dr Jin Rui Liang, University of Dundee
Understanding the Roles of ERphagy during Epithelial-to-Mesenchymal Transition

伦敦大学学院癌症研究所Simone Zaccaria博士
在单细胞全基因组分辨率下的进化起源和转移途径的深入表征

职业机构奖

Dr Seth Coffelt, University of Glasgow
Defining WNT/beta-catenin control over immunosurveillance and immune escape in colon cancer

伦敦帝国学院路易丝·菲茨博士
Understanding how membrane transporters influence variability in cancer drug uptake and investigating implications for efficacy

Senior Cancer Research Fellowship

Dr J. Ross Chapman, University of Oxford
癌症同源重组缺乏的明显表现的机制

临床医生奖学金

Dr Sarah Gooding, University of Oxford
Exploiting recurrent chromosome copy number alteration (CNA)-driven defects in the treatment of Multiple Myeloma

临床试验奖学金

Dr Chris Williams & Dr David Cairns, University of Leeds
利兹CRUK临床试验单元的临床试验中广泛培训计划,重点是结直肠癌的生物标志物驱动试验

苏菲·梅里克(Sophie Merrick)博士和伦敦大学学院邓肯·吉尔伯特(Dr. Duncan Gilbert)博士
Optimising immuno-oncology approaches in oncology

利兹大学Finbar Slevin博士和Sarah Brown博士
188金宝搏app亚洲英国癌症研究Clinical Trials Unit at Leeds Fellowship – developing a future chief investigator of advanced radiotherapy clinical trials

Pre-doctoral Research Bursaries

Dr Danyal Zaman Khan, University College London
使用人工智能对垂体肿瘤的个性化,数据驱动的手术管理 - 一项试点研究

伦敦帝国学院的安东尼奥·德阿莱西奥博士
Integrated characterisation of anti-tumour immunity following neoadjuvant immunotherapy of hepatocellular carcinoma

CRUK病态学会前研究助学金

谢菲尔德大学保罗·汉金森博士
唾液细胞外囊泡作为口腔上皮发育不创的非侵入性生物标志物的利用

More facts and figures about our research funding

Facts and figures about our research funding

Find out more about how and where we supported research in the last year with our interactive map and infographics.

Funding committees

我们的委员会监督对CRUK资金申请的同行评审,并支持提供我们战略优先事项的交付。

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